Report on a patient with bleeding angiodysplasia of the ascending colon. The clinical course was characteristic for this kind of lesions: long-term, chronic, recurrent intestinal hemorrhages with a gradual increase of anemia. Diagnosis was complicated by lack of success in finding the source of the hemorrhage and by evidence of various pathological findings. Histologically, there were vessel variations typical for angiodysplasia and, furthermore, cholesterol emboli of the submucosal colic arteries. The latter's pathogenetic role as trigger for the hemorrhage is discussed.