Crossed cerebellar diaschisis in ischemic stroke: a study of regional cerebral blood flow by 133Xe inhalation and single photon emission computerized tomography

J Cereb Blood Flow Metab. 1984 Jun;4(2):235-40. doi: 10.1038/jcbfm.1984.32.


Seventy measurements of CBF were performed in 12 stroke patients by 133Xe inhalation and a rapidly rotating single photon emission computerized tomograph. CBF was measured every other day during the acute phase and at 2- and 6-month follow-up visits. A persistent contralateral cerebellar blood flow depression was evident in five patients with severe hemispheric low flow areas, which correlated with large, hypodense lesions on the computerized tomographic scan. In a sixth patient with a small, deep infarct, a transient crossed cerebellar low flow was observed, while the clinical symptoms persisted. It is concluded from this serial study that crossed cerebellar diaschisis is a common finding in completed stroke. It is probably caused by disconnection of the corticopontine pathways, a disconnection that tends to persist. The phenomenon is in fact less variable than the stroke-related CBF changes in the infarcted hemisphere, in which a period of relative hyperemia is frequently seen.

MeSH terms

  • Adult
  • Aged
  • Brain Ischemia / diagnostic imaging
  • Brain Ischemia / metabolism*
  • Cerebellar Diseases / diagnostic imaging
  • Cerebellar Diseases / metabolism*
  • Cerebrovascular Circulation*
  • Cerebrovascular Disorders / diagnostic imaging
  • Cerebrovascular Disorders / metabolism*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Tomography, Emission-Computed*
  • Xenon Radioisotopes


  • Xenon Radioisotopes