Abstract
DNA clones specifying the murine granulocyte-macrophage colony stimulating factor have been isolated. This haematopoietic growth factor is encoded by a unique gene specifying a messenger RNA of 1,200 nucleotides and a polypeptide of 118 amino acids. It bears no structural similarity to the functionally related factor, interleukin-3, described recently.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Amino Acid Sequence
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Animals
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Base Sequence
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Cloning, Molecular*
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Colony-Stimulating Factors / genetics*
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DNA / metabolism*
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Female
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Fetus
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Genes*
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Growth Substances / genetics
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Kinetics
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Liver / physiology
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Lung / metabolism
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Mice
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Oocytes / metabolism
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RNA, Messenger / genetics
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Transcription, Genetic
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Xenopus
Substances
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Colony-Stimulating Factors
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Growth Substances
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RNA, Messenger
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DNA