Molecular cloning of cDNA encoding a murine haematopoietic growth regulator, granulocyte-macrophage colony stimulating factor

Nature. 1984;309(5971):763-7. doi: 10.1038/309763a0.

Abstract

DNA clones specifying the murine granulocyte-macrophage colony stimulating factor have been isolated. This haematopoietic growth factor is encoded by a unique gene specifying a messenger RNA of 1,200 nucleotides and a polypeptide of 118 amino acids. It bears no structural similarity to the functionally related factor, interleukin-3, described recently.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Cloning, Molecular*
  • Colony-Stimulating Factors / genetics*
  • DNA / metabolism*
  • Female
  • Fetus
  • Genes*
  • Growth Substances / genetics
  • Kinetics
  • Liver / physiology
  • Lung / metabolism
  • Mice
  • Oocytes / metabolism
  • RNA, Messenger / genetics
  • Transcription, Genetic
  • Xenopus

Substances

  • Colony-Stimulating Factors
  • Growth Substances
  • RNA, Messenger
  • DNA

Associated data

  • GENBANK/X05906