A unified model for complex segregation analysis

Am J Hum Genet. 1983 Sep;35(5):816-26.

Abstract

Various methods have been proposed for statistical inference of major genes by segregation analysis of human familial data. An attempt is made to resolve some divergences that have occurred in this context by the consideration of a unified model, with some practical applications.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Alleles
  • Cholesterol / blood
  • Gene Frequency
  • Genetics, Medical*
  • Humans
  • Immunoglobulin E / genetics
  • Magnesium / blood
  • Meiosis
  • Models, Genetic*
  • Phenotype
  • Probability

Substances

  • Immunoglobulin E
  • Cholesterol
  • Magnesium