Megacystis-microcolon-intestinal hypoperistalsis syndrome in a newborn girl whose brother had prune belly syndrome: common pathogenesis?

Pediatr Radiol. 1983;13(5):294-6. doi: 10.1007/BF00973353.


A case of megacystis-microcolon-intestinal hypoperistalsis syndrome (MMIHS) is presented. There were important findings: a urachal remnant and a brother with prune belly syndrome (PBS). After a review of the literature, many common characteristics of MMIHS and PBS are described: flaccid abdomen, dilatation of the urinary tract, intestinal malrotation, cryptorchidism, urachal remnants and familial incidence. MMIHS and PBS may be manifestations of the same underlying process.

Publication types

  • Case Reports

MeSH terms

  • Abnormalities, Multiple*
  • Colon / abnormalities*
  • Colon / diagnostic imaging
  • Female
  • Gastrointestinal Motility*
  • Humans
  • Infant, Newborn
  • Male
  • Peristalsis*
  • Prune Belly Syndrome / genetics*
  • Radiography
  • Urinary Bladder / abnormalities*
  • Urinary Bladder / diagnostic imaging