Hemodynamics during experimental gastric dilatation-volvulus in dogs

Am J Vet Res. 1983 Aug;44(8):1512-5.


Gastric dilatation-volvulus (at 30 mm of Hg of gastric pressure) was experimentally induced in 8 dogs under sodium pentobarbital anesthesia. Hemodynamic indices including cardiac output, mean aortic pressure, left ventricular end diastolic pressure, heart rate, total peripheral resistance, and dp/dtmax were measured during a 180-minute period of gastric dilatation-volvulus and for 120 minutes after gastric decompression. Experimental gastric dilatation-volvulus resulted in significant (P less than 0.05) decreases in cardiac output (64%), mean aortic pressure (48%), left ventricular end diastolic pressure (68%), and ventricular dp/dtmax (32%) compared to 4 control dogs. Hemodynamic indices returned toward control values after gastric decompression. It was concluded that gastric dilatation-volvulus in the present experiment was capable of inducing hemodynamic alterations of a magnitude similar to those reported in gastric dilatation studies, using higher gastric pressures.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Decompression / veterinary
  • Dog Diseases / physiopathology*
  • Dogs
  • Female
  • Gastric Dilatation / complications
  • Gastric Dilatation / physiopathology
  • Gastric Dilatation / veterinary*
  • Hemodynamics*
  • Ischemia / complications
  • Ischemia / veterinary
  • Male
  • Myocardial Contraction
  • Pancreas / blood supply
  • Pressure
  • Stomach / blood supply
  • Stomach Volvulus / complications
  • Stomach Volvulus / physiopathology
  • Stomach Volvulus / veterinary*