Pharmacokinetics of caffeine during and after pregnancy

Dev Pharmacol Ther. 1983;6(5):315-22. doi: 10.1159/000457332.


The pharmacokinetic parameters of caffeine were measured in 9 pregnant women and 4 women 4 days post partum. The results show a significant prolongation of caffeine elimination in pregnant women. Normal pharmacokinetic parameters seem to be restored as soon as 4 days post partum. Steroids hormones (estriol, estradiol, and progesterone) were measured in both cases.

MeSH terms

  • Adult
  • Caffeine / metabolism*
  • Female
  • Humans
  • Kinetics
  • Postpartum Period*
  • Pregnancy*
  • Regression Analysis


  • Caffeine