Cholesterol screening in childhood: does it predict adult hypercholesterolemia? The Beaver County experience

J Pediatr. 1983 Nov;103(5):687-91. doi: 10.1016/s0022-3476(83)80458-2.


To establish the value of screening children for hypercholesterolemia in terms of identifying future adults with hypercholesterolemia, we studied 611 individuals 9 years after they were initially screened at age 12 years. They represent 61% of a stratified sample of the original cohort, which was drawn from all seventh graders in a countywide school district. Overall, the correlation between baseline and follow-up cholesterol concentration was r = 0.52 (P less than 0.0001). Forty-nine percent of the top cholesterol quintile at baseline were similarly placed at follow-up, with 70% in the top two quintiles. Children who dropped out of the top quintile had lower body mass index at follow-up (P less than 0.05), were less frequently smokers, and tended to be more active than those who were only in the top quintile as adults.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • Body Composition
  • Child
  • Cholesterol / blood*
  • Diet
  • Female
  • Humans
  • Hypercholesterolemia / epidemiology*
  • Life Style
  • Male
  • Mass Screening*
  • Probability
  • Smoking


  • Cholesterol