Native American medicinal plants. Anemonin from the horse stimulant Clematis hirsutissima

J Ethnopharmacol. 1983 Jul;8(1):121-3. doi: 10.1016/0378-8741(83)90093-4.


Anemonin, the dilactone of cyclobutane-1,2-diol-1,2-diacrylic acid derived from the cyclodimerization of protoanemonin, a known blistering agent, was isolated from Clematis hirsutissima, a plant used by the Nez Perce and Teton Sioux nations as a horse stimulant.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Furans*
  • Horses / physiology
  • Plants, Medicinal / analysis*
  • Terpenes / isolation & purification*
  • Terpenes / pharmacology
  • United States


  • Furans
  • Terpenes
  • anemonin