Model-free Deconvolution Techniques for Estimating Vascular Transport Functions

Int J Biomed Comput. 1983 Sep;14(5):411-29. doi: 10.1016/0020-7101(83)90024-7.


In this paper we present two methods which can be used to numerically deconvolve indicator dilution curves to obtain vascular transport functions. In the first method, direct algebraic deconvolution is made stable and practical by the damped least squares method. The second method involves a time-shift of the output curve which is based on the first and second moments of the input and output curves. This method is stable, computationally simple and can provide reasonable estimates of the transport function.

Publication types

  • Comparative Study
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Blood Circulation Time
  • Dogs
  • Hemodynamics*
  • In Vitro Techniques
  • Statistics as Topic*