The importance of internal quality control data in National External Quality Assessment schemes. Plasma progesterone assays

Stat Med. 1983 Apr-Jun;2(2):123-9. doi: 10.1002/sim.4780020205.

Abstract

Co-ordinators of external quality assessment schemes in the U.K. despatch samples of quality control material to participant laboratories at frequent intervals to assess laboratory performance. We show, via a controlled experiment on the plasma progesterone assay, that the current analysis performed by the external assessors is inadequate and often leads to erroneous conclusions about a laboratory's performance. It is concluded that for a proper assessment of a laboratory's performance, the external assessor should prepare large pools of plasma and distribute them to all participants in the scheme to use as internal quality control material.

Publication types

  • Comparative Study

MeSH terms

  • Chemistry Techniques, Analytical
  • Humans
  • Laboratories
  • Progesterone / blood*
  • Quality Control
  • Reference Standards

Substances

  • Progesterone