Pulmonary excretion of methanol in man

Scand J Clin Lab Invest. 1983 Sep;43(5):377-9. doi: 10.1080/00365518309168275.


An otherwise healthy methanol-poisoned male was treated with ethanol and forced diuresis. No acidosis or visual symptoms occurred. His blood ethanol concentrations varied between 10.7 and 30.0 mmol/l (0.49-1.38 g/l). His maximal blood methanol concentration was 14.4 mmol/l (0.45 g/l) and his plasma formate levels were within reference range (0.11-0.29 mmol/l). In a 24 h period where methanol metabolism was blocked by ethanol, the total body clearance and renal clearance of methanol were 11.3 and 5.7 ml/min, respectively. The difference, 5.6 ml/min, to a large extent reflects the pulmonary clearance of methanol thus being low in man.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Ethanol / blood
  • Ethanol / therapeutic use
  • Formates / blood
  • Humans
  • Lung / metabolism*
  • Male
  • Methanol / metabolism*
  • Methanol / poisoning


  • Formates
  • Ethanol
  • Methanol