Carcinoma in situ in testicular biopsies from men presenting with infertility

Br J Urol. 1983 Dec;55(6):780-4. doi: 10.1111/j.1464-410x.1983.tb03425.x.


This study concerns 2043 male partners of infertile marriages who underwent testicular biopsy in the 28 years from 1955 to 1982. In a review of the pathological material carcinoma in situ (CIS) was diagnosed in 8 men (0.39%). Six of these men were later found to have invasive germ cell tumours; one has remained tumour-free and one is lost to follow-up. The implication of these findings in relation to the selection of patients for biopsy and the treatment of CIS when diagnosed is discussed.

MeSH terms

  • Adult
  • Biopsy
  • Carcinoma in Situ / complications*
  • Carcinoma in Situ / pathology
  • Humans
  • Infertility, Male / etiology*
  • Male
  • Testicular Neoplasms / complications*
  • Testicular Neoplasms / pathology
  • Testis / pathology