25 men and 25 women with ankylosing spondylitis were interviewed, using a structural questionnaire, covering a profile of the disease and of socioeconomic areas. Particular attention was paid to sexual activity, pregnancy and child-rearing. Significant problems in most areas asked about were found, although childbearing was not curtailed. Tiredness was responsible for a lot of disability but the women managed housework reasonably well and also had a fairly good employment record.