The gene organisation of a small RNA-containing insect virus: comparison with that of mammalian picornaviruses

Virology. 1983 Dec;131(2):551-4. doi: 10.1016/0042-6822(83)90520-2.

Abstract

The coding regions of an insect virus, cricket paralysis virus, have been mapped using pactamycin. The results suggest that the genome of this virus functions as a polycistronic mRNA, the structural proteins being encoded by the 5' end of the RNA in an order similar to those of mammalian picornaviruses. High-molecular-weight proteins of unknown function map at the 3' end of the genome.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Chromosome Mapping
  • Genes, Viral* / drug effects
  • Insect Viruses / drug effects
  • Insect Viruses / genetics*
  • Mammals / microbiology*
  • Pactamycin / pharmacology
  • Picornaviridae / drug effects
  • Picornaviridae / genetics*
  • RNA Viruses / drug effects
  • RNA Viruses / genetics*
  • RNA, Viral / genetics

Substances

  • RNA, Viral
  • Pactamycin