Effects of oxygen concentration on biomass production, maximum specific growth rate and extracellular enzyme production by three species of cutaneous propionibacteria grown in continuous culture

J Gen Microbiol. 1983 Nov;129(11):3327-34. doi: 10.1099/00221287-129-11-3327.


Propionibacterium acnes, Propionibacterium avidum and Propionibacterium granulosum were grown in continuous culture at 0-100% air saturation using a semi-synthetic medium. Maximum specific growth rate, biomass concentration and extracellular lipase, hyaluronate lyase and phosphatase activities were determined. All three species were capable of growth at 100% air saturation but at reduced growth rates. The presence of oxygen altered the production of extra-cellular enzymes. Propionibacterium avidum was the best adapted for growth in aerobic environments.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acid Phosphatase / biosynthesis
  • Bacterial Proteins / biosynthesis
  • Ecology
  • Humans
  • Lipase / biosynthesis
  • Oxygen / pharmacology*
  • Polysaccharide-Lyases / biosynthesis
  • Propionibacterium / enzymology
  • Propionibacterium / growth & development*
  • Propionibacterium acnes / enzymology
  • Propionibacterium acnes / growth & development
  • Protein Denaturation
  • Skin / microbiology*
  • Species Specificity


  • Bacterial Proteins
  • Lipase
  • Acid Phosphatase
  • Polysaccharide-Lyases
  • hyaluronate lyase
  • Oxygen