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Case Reports
. 1978 Jul;188(1):53-9.
doi: 10.1097/00000658-197807000-00009.

Cloacogenic carcinoma

J D Sink, S A Kramer, D D Copeland, H F Seigler
Case Reports

Cloacogenic carcinoma

J D Sink et al. Ann Surg. 1978 Jul.

Abstract

Cloacogenic carcinoma is a rare tumor of the anorectal region originating from a persistant remnant of the cloacal membrane of the embryo. The tumor accounts for 2-3% of anorectal carcinomas and occurs more than twice as often in women. Most tumors present as fungating or ulcerating lesions, but the tumor may arise in anal ducts and present as a submucosal mass. Wide abdominoperineal resection is the treatment of choice with a five year survival of 50%. Metastases occurs to the inguinal lymph nodes in more than 50% of the patients at sometime during the course of the disease with distant metastases occuring most commonly to liver and lungs.

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