Epidemiologic study of amyotrophic lateral sclerosis in Sardinia, Italy

Acta Neurol Scand. 1983 Dec;68(6):394-404. doi: 10.1111/j.1600-0404.1983.tb04849.x.


From 1957 to 1980 in Sardinia, 182 cases of ALS with a mean annual incidence of 0.51 per 100,000 inhabitants and a prevalence rate of 3.65 per 100,000 inhabitants (prevalence day 21.10.1971) were observed. The disease was found to be more common in males, in subjects aged 50 to 70 years and in farmers and shepherds. Incidence in various areas of the island was found to be different. The common form was more frequent, had earlier onset and greater median survival rate.

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Aged
  • Amyotrophic Lateral Sclerosis / epidemiology*
  • Amyotrophic Lateral Sclerosis / mortality
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Infant
  • Infant, Newborn
  • Italy
  • Male
  • Middle Aged
  • Sex Factors