Selective inhibition of RNA polyadenylation by Ara-ATP in vitro: a possible mechanism for antiviral action of Ara-A

Biochem Biophys Res Commun. 1978 Apr 28;81(4):1418-24. doi: 10.1016/0006-291x(78)91294-9.
No abstract available

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Adenosine Triphosphate / metabolism
  • Animals
  • Binding, Competitive
  • Cell Nucleus / enzymology
  • Chromatin / metabolism
  • Kinetics
  • Liver / ultrastructure
  • Male
  • Nucleotidyltransferases / antagonists & inhibitors*
  • Polynucleotide Adenylyltransferase / antagonists & inhibitors*
  • RNA / biosynthesis
  • Rats
  • Solubility
  • Vidarabine / analogs & derivatives*
  • Vidarabine / pharmacology
  • Vidarabine Phosphate / analogs & derivatives

Substances

  • Chromatin
  • Vidarabine Phosphate
  • ara-ATP
  • RNA
  • Adenosine Triphosphate
  • Nucleotidyltransferases
  • Polynucleotide Adenylyltransferase
  • Vidarabine