The antimicrobial activity of garlic and onion extracts

Pharmazie. 1983 Nov;38(11):747-8.


Aqueous extracts of garlic (Allium sativum) and onion (Allium cepa) were tested for activity against Gram-positive organisms, Gram-negative organisms and fungi. A significant growth inhibition was shown by most of the organisms, tested at random. A quantitative assessment of the activity was carried out by determining the minimum bacteriostatic and bactericidal concentrations of the extracts against Gram-positive and Gram-negative organisms. Garlic extract showed greater activity as compared to the extract of onion. The activity of the garlic extract on the mouth flora of volunteers was then investigated. A mouth wash containing 10% garlic in quarter Ringer solution produced a drastic reduction in the number of oral bacteria.

MeSH terms

  • Anti-Bacterial Agents*
  • Bacteria / drug effects
  • Garlic*
  • Gram-Negative Bacteria / drug effects
  • Gram-Positive Bacteria / drug effects
  • Humans
  • Microbial Sensitivity Tests
  • Mouth / microbiology
  • Plant Extracts / pharmacology*
  • Plants, Medicinal*


  • Anti-Bacterial Agents
  • Plant Extracts