[Collective acute poisoning by nitrous gases]

Toxicol Eur Res. 1983 Sep;5(5):220-4.
[Article in French]

Abstract

A collective nitrous fumes poisoning (five cases) is reported. Two patients (case 3 and case 4) were comatose, in severe respiratory distress. Shock and slate blue cyanosis were noted. Physical examination and chest X ray revealed acute pulmonary edema-Methemoglobin levels were 71,3% (case 3) and 58% (case 4). Despite treatment both of them died from severe hypoxia resulting in cardiorespiratory arrest. Post-mortem examination was performed upon these four men. On admission the last one (case 5) was conscious, and in good hemodynamic condition. Acute pulmonary edema and cyanosis were present. Methemoglobin level was 37,3%. This patient recovered appropriate therapy. For case 1 and 2 acute anoxia due to methemoglobinemia seems to be cause of death. For cases 3 and 4 death is due to hypoxemia associated with pulmonary edema.

Publication types

  • Case Reports

MeSH terms

  • Accidents, Occupational*
  • Bronchi / pathology
  • Cyanosis / chemically induced
  • Hemodynamics
  • Humans
  • Lung / diagnostic imaging
  • Lung / pathology
  • Methemoglobinemia / chemically induced
  • Nitrates
  • Nitrogen Dioxide
  • Nitrogen Oxides / poisoning*
  • Occupational Diseases / chemically induced*
  • Pulmonary Edema / chemically induced
  • Radiography
  • Water-Electrolyte Imbalance / chemically induced

Substances

  • Nitrates
  • Nitrogen Oxides
  • Nitrogen Dioxide
  • ammonium nitrate