Fatal pulmonary fibrosis following 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) therapy

Cancer. 1978 Jul;42(1):74-6. doi: 10.1002/1097-0142(197807)42:1<74::aid-cncr2820420111>3.0.co;2-i.

Abstract

A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy. This side effect has only once previously been reported with the nitrosourea group of compounds.

Publication types

  • Case Reports

MeSH terms

  • Carmustine / adverse effects*
  • Cerebellar Neoplasms / drug therapy*
  • Female
  • Humans
  • Infant
  • Medulloblastoma / drug therapy*
  • Pneumonia, Pneumococcal / complications
  • Pulmonary Fibrosis / chemically induced*
  • Pulmonary Fibrosis / complications
  • Pulmonary Fibrosis / pathology

Substances

  • Carmustine