Serum lipids and lipoprotein concentrations in women with rheumatoid arthritis

Clin Rheumatol. 1983 Dec;2(4):387-91. doi: 10.1007/BF02041560.


Serum lipid and lipoprotein concentrations were measured in 51 women with rheumatoid arthritis treated with both nonsteroidal and steroidal drugs and compared to a group of women with rheumatoid arthritis not receiving anti-inflammatory drugs and to a healthy control group. Significantly lower concentrations of total cholesterol and low density lipoprotein cholesterol were found in the rheumatoid patients on nonsteroidal or steroidal anti-inflammatory drugs, while no difference was found in high density lipoprotein cholesterol and triglycerides. In the group of rheumatoid patients who received no nonsteroidal or steroidal anti-inflammatory drugs, the triglyceride level was higher than in the control group, and that of HDL-C was lower. Total cholesterol and LDL-C levels were higher in the patients not on anti-inflammatory drugs than in patients receiving anti-inflammatory drugs. The results of this study suggest that hyperlipidemia is not one of the predisposing factors for coronary disease in patients with rheumatoid arthritis receiving anti-inflammatory therapy. Anti-inflammatory drugs may play a role in the regulation of serum lipids in patients with rheumatoid arthritis.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Anti-Inflammatory Agents / therapeutic use
  • Arthritis, Rheumatoid / blood*
  • Arthritis, Rheumatoid / drug therapy
  • Cholesterol / blood
  • Coronary Disease / etiology
  • Disease Susceptibility
  • Female
  • Humans
  • Lipids / blood*
  • Lipoproteins / blood*
  • Middle Aged
  • Phospholipids / blood
  • Triglycerides / blood


  • Anti-Inflammatory Agents
  • Lipids
  • Lipoproteins
  • Phospholipids
  • Triglycerides
  • Cholesterol