Asthma, allergy and bronchial hyper-reactivity to histamine in patients with bronchiectasis

Clin Allergy. 1978 May;8(3):273-80. doi: 10.1111/j.1365-2222.1978.tb03224.x.


An allergy examination was made on forty-eight consecutive bronchiectasis patients, with a mean age of 37 years. Eleven had confirmed asthma and another nine, making twenty in all (42%), had distinct allergic diathesis. Allergy to a specific allergen was established in five cases. 50% of the patients in the total series had bronchial histamine hyper-reactivity, eleven without asthma or distinct allergic diathesis. The results corroborate views previously reported of the role of asthmatic symptoms and allergic diathesis as aetiological factors of bronchiectasis.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Asthma / immunology*
  • Bronchi / drug effects
  • Bronchi / immunology*
  • Bronchiectasis / immunology*
  • Female
  • Histamine / pharmacology*
  • Humans
  • Male
  • Middle Aged
  • Respiratory Hypersensitivity / immunology*
  • Rhinitis, Allergic, Seasonal / immunology


  • Histamine