Two cases of encephalo-angiomatosis are reported. The clinical presentation and certain neurological findings and investigations confirm the diagnosis of a disease which is relatively rare among Blacks. The case reports were considered valuable because of the rareness of the condition. Up to 1962 only 145 cases had been reported in the world literature. Encephalo-angiomatosis or Sturge-Weber syndrome is one of the disease groups known as phakomatoses, and an attempt is made to characterize each phakomatosis condition.