[Comparison of the antihypoxic effect of alpha-tocopherol, NAD and inosine during prolonged artificial circulation]

Farmakol Toksikol. 1984 Jan-Feb;47(1):88-93.
[Article in Russian]


Mathematical analysis was used to compare the antihypoxic action of alpha-tocopherol, inosine and oxidized NAD under long-term extracorporeal circulation. Of the drugs studied, oxidized NAD form was demonstrated to be the most active, inosine appeared less active, and alpha-tocopherol still less active. It is advisable to study more thoroughly the effect of oxidized NAD under long-term extracorporeal circulation.

Publication types

  • Comparative Study

MeSH terms

  • Animals
  • Drug Evaluation, Preclinical
  • Extracorporeal Circulation*
  • Hemodynamics / drug effects
  • Hypoxia / prevention & control*
  • Inosine / therapeutic use*
  • Mathematics
  • NAD / therapeutic use*
  • Time Factors
  • Vitamin E / therapeutic use*


  • NAD
  • Vitamin E
  • Inosine