The protective effect of auto-immune buccal urine therapy (AIBUT) against the Raynaud phenomenon

Med Hypotheses. 1984 Jan;13(1):99-107. doi: 10.1016/0306-9877(84)90133-6.


The efficacy of Auto-Immune Buccal Urine Therapy (AIBUT) against allergic symptoms depends upon sublingual administration of the correct dose of urine as determined by bio-assay in individual patients. Succeeding effective turn-off doses occur at the troughs of a sinusoidal dose-response curve. Efficacy of the administered dose is confirmed by reduction in the severity and duration of Cold-water-induced Raynaud symptoms after administration of effective doses of unboiled urine in AIBUT. Boiled urine does not affect the Raynaud phenomenon.

Publication types

  • Case Reports

MeSH terms

  • Administration, Oral
  • Adolescent
  • Adult
  • Allergens / administration & dosage*
  • Desensitization, Immunologic / methods*
  • Dose-Response Relationship, Drug
  • Female
  • Food Hypersensitivity / immunology
  • Humans
  • Male
  • Middle Aged
  • Raynaud Disease / therapy*
  • Self Administration
  • Taste
  • Urine*


  • Allergens