Alternative transcription and two modes of splicing results in two myosin light chains from one gene

Nature. 1984 Mar;308(5957):333-8. doi: 10.1038/308333a0.

Abstract

Chicken skeletal muscle myosin alkali light chains are encoded by a single gene of size 18 kilobases (kb). This gene has two transcription initiation sites from which 17.5- and 8-kb precursor RNAs are transcribed. These RNAs are processed by different modes of splicing to form mRNAs encoding distinct light-chain (LC1 and LC3) proteins.

MeSH terms

  • Animals
  • Chickens / genetics
  • Chromosome Mapping
  • Gene Expression Regulation
  • Genes
  • Myosins / genetics*
  • RNA Splicing*
  • RNA, Messenger / genetics
  • Transcription, Genetic

Substances

  • RNA, Messenger
  • Myosins

Associated data

  • GENBANK/K02608
  • GENBANK/K02609
  • GENBANK/K02610