Regional distribution of ventilation-perfusion ratios in acute pulmonary embolism

Intensive Care Med. 1984;10(2):103-6. doi: 10.1007/BF00297567.


Regional ventilation perfusion ratios have been computed in 44 patients with acute pulmonary embolism with a gamma-camera using Krypton 81m, a short-life radionuclide delivered by inhalation and infusion. This noninvasive technique is performed during tidal breathing and can be easily repeated. High V/Q's are detected in the embolic regions and low V/Q's in the nonembolic regions with a shift of the perfusion distribution towards these low values. This pattern disappears with recovery. This technique can be used in clinical practice for diagnostic purposes.

MeSH terms

  • Acute Disease
  • Angiography
  • Humans
  • Krypton
  • Pulmonary Artery / diagnostic imaging
  • Pulmonary Embolism / diagnostic imaging*
  • Pulmonary Embolism / physiopathology
  • Radioisotopes
  • Radionuclide Imaging
  • Ventilation-Perfusion Ratio*


  • Radioisotopes
  • Krypton