Multiple evanescent white dot syndrome. I. Clinical findings

Arch Ophthalmol. 1984 May;102(5):671-4. doi: 10.1001/archopht.1984.01040030527008.


We examined 11 young patients with unilateral ocular findings that included multiple white dots at the level of the retinal pigment epithelium (RPE) or the deep retina, vitreal cells, RPE granularity in the macula, reduced visual acuity, electroretinogram (ERG) and early receptor potential (ERP) amplitudes, and fluorescein leakage from disc capillaries and late staining of the RPE. Recovery of visual function included a dramatic improvement in ERG and ERP amplitudes over several weeks. The etiology of this syndrome remains uncertain; there is no definite evidence of systemic involvement.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • Electroretinography
  • Evoked Potentials, Visual
  • Female
  • Fluorescein Angiography
  • Humans
  • Macula Lutea / pathology
  • Male
  • Pigment Epithelium of Eye / pathology*
  • Retina / pathology*
  • Retinal Diseases / diagnosis*
  • Retinal Diseases / pathology
  • Retinal Vein / pathology
  • Syndrome
  • Visual Acuity
  • Vitreous Body / pathology