Characterization of the ATP-G-actin aggregates formed at low potassium chloride concentration

Biochem J. 1984 Apr 1;219(1):273-6. doi: 10.1042/bj2190273.

Abstract

The ATP-G-actin aggregates formed by incubation of ATP-G-actin in 7.5 mM-KCl were characterized by electron-microscopical observation, by high-pressure liquid chromatography and by the study of the 1,N6-etheno-ATP-ATP exchange reaction between the free and the actin-bound nucleotide. In 30 mM-KCl the initial rate of the reduced-viscosity increase is found to be directly related to the amount of the aggregates formed in the course of the preincubation in 7.5 mM-KCl.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Actins*
  • Adenosine Triphosphate*
  • Chromatography, High Pressure Liquid
  • Ethenoadenosine Triphosphate
  • Macromolecular Substances
  • Microscopy, Electron
  • Potassium Chloride
  • Protein Binding

Substances

  • Actins
  • Ethenoadenosine Triphosphate
  • Macromolecular Substances
  • Potassium Chloride
  • Adenosine Triphosphate