Lymphomatoid granulomatosis with isolated involvement of the brain

Ann Neurol. 1984 May;15(5):478-81. doi: 10.1002/ana.410150513.


A patient with biopsy-proven lymphomatoid granulomatosis of the brain as the sole manifestation of the disease is described. During 14 months of follow-up since surgical excision of the cerebral mass, no evidence of recurrent brain involvement or of extracranial lesions has been found. This case is unusual in the confinement of the disease to the central nervous system and in the favorable outcome following surgical treatment alone.

Publication types

  • Case Reports

MeSH terms

  • Brain Neoplasms / pathology*
  • Brain Neoplasms / surgery
  • Cerebral Cortex*
  • Cyclophosphamide / administration & dosage
  • Drug Therapy, Combination
  • Humans
  • Lymphomatoid Granulomatosis / drug therapy
  • Lymphomatoid Granulomatosis / pathology*
  • Lymphomatoid Granulomatosis / surgery
  • Male
  • Middle Aged
  • Prednisone / administration & dosage
  • Prognosis


  • Cyclophosphamide
  • Prednisone