A logical approach to the treatment of massive periretinal proliferation

Ophthalmology. 1978 Jun;85(6):584-93. doi: 10.1016/s0161-6420(78)35637-2.


Based on the improved understanding of massive periretinal proliferation (MPP) as a proliferative membrane-forming disease, a new therapeutic approach is presented with the technique of pars plana vitreous surgery. Not only vitreous membranes but also preretinal membranes are removed. Forty-seven consecutive patients who suffered from severe massive periretinal proliferation were operated on with this technique and followed for six months or more. Seventeen patients (36%) had an attached retina. Twelve patients had a major visual improvement. The major postoperative complication was phthisis bulbi, found in ten eyes (21%).

Publication types

  • Case Reports
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Aged
  • Follow-Up Studies
  • Hemorrhage / etiology
  • Humans
  • Male
  • Membranes / surgery
  • Methods
  • Postoperative Complications
  • Retina / injuries
  • Retina / surgery*
  • Retinal Detachment / complications
  • Retinal Detachment / surgery
  • Retinal Diseases / surgery*
  • Scleral Buckling
  • Surgical Procedures, Operative / adverse effects
  • Visual Acuity
  • Vitreous Body / surgery*