Plant anticancer agents XXIX. Cleomiscosin A from Simaba multiflora, Soulamea soulameoides, and Matayba arborescens

J Nat Prod. 1984 Mar-Apr;47(2):300-7. doi: 10.1021/np50032a011.

Abstract

Cleomiscosin A (1) has been isolated from Simaba multiflora and Soulamea soulameoides in the Simaroubaceae through bioactivity-directed fractionation and from Matayba arborescens in the Sapindaceae . The structure of cleomiscosin A (1) was established through spectroscopic studies and chemical reactions.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Acetylation
  • Animals
  • Antineoplastic Agents, Phytogenic / isolation & purification*
  • Cell Line
  • Chemical Phenomena
  • Chemistry
  • Coumarins
  • Dioxanes / isolation & purification*
  • Dioxanes / pharmacology
  • Dioxins / isolation & purification*
  • Humans
  • Leukemia P388 / drug therapy
  • Methylation
  • Mice
  • Molecular Weight
  • Nasopharyngeal Neoplasms
  • Plant Extracts / analysis

Substances

  • Antineoplastic Agents, Phytogenic
  • Coumarins
  • Dioxanes
  • Dioxins
  • Plant Extracts
  • cleomiscosin A