Pneumonitis, pleural effusion and pericarditis following treatment with dantrolene

J Neurol Neurosurg Psychiatry. 1984 May;47(5):553-4. doi: 10.1136/jnnp.47.5.553.


A patient developed pulmonary infiltration, pleural effusions and pericarditis three months after starting dantrolene sodium. Peripheral blood eosinophilia and a raised ESR were present. Symptoms and signs resolved after the drug was discontinued. Dantrolene toxicity should be considered in the differential diagnosis of pneumonitis and pleuro-pericarditis.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Dantrolene / adverse effects*
  • Female
  • Humans
  • Muscle Spasticity / drug therapy
  • Pericarditis / chemically induced*
  • Pleural Effusion*
  • Pneumonia / chemically induced*
  • Radiography, Thoracic


  • Dantrolene