Red-cell auto-antibodies mimicking anti-Fyb specificity

Vox Sang. 1984;47(1):88-91. doi: 10.1111/j.1423-0410.1984.tb01566.x.


An antibody is described, produced by an Fy(a+b-) woman that at first reacted with her own cells, preferentially with Fy(b+) cells but not with Fy(a-b-) cells. Later, pure anti-Fyb specificity occurred. Elution and absorption studies revealed that the antibody recognized a determinant absent from Fy(a-b-) cells but present on Fy(a+b-) and Fy(a-b+) cells, much more strongly, however, on the latter, and that it was an autoantibody.

Publication types

  • Case Reports

MeSH terms

  • Anemia, Hemolytic, Autoimmune / etiology
  • Antibody Specificity
  • Autoantibodies / immunology*
  • Blood Group Antigens / immunology*
  • Blood Grouping and Crossmatching
  • Coombs Test
  • Duffy Blood-Group System / immunology*
  • Erythrocytes / immunology*
  • Female
  • Humans
  • Middle Aged
  • Transfusion Reaction


  • Autoantibodies
  • Blood Group Antigens
  • Duffy Blood-Group System