The video-ophthalmograph records the topography of the optic disk via simultaneous stereoscopic images which are stored and analyzed with the help of a microcomputer. This information is used to generate the vertical cup-disk ratio, the vertical optic disk diameter, the cup volume, and the neuroretinal rim area. To determine the reliability of the data, we recorded information for one eye of each of five patients ten times to determine the interphotographic error variance. We also analyzed one photograph for each of five patients ten times to determine the intraphotographic variance attributable to repeated analysis of the same photograph. The interphotographic and intraphotographic coefficients of variation were 2% to 18% and 2% to 7% respectively for these measurements.