Abstract
Serological analysis of white blood cells from the members of a family of American cocker spaniels indicates that a form of abnormal sexual development, in which individuals with a female karyotype have testes or ovotestes, is caused by anomalous transmission of male-determining H-Y genes.
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Animals
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Cell Differentiation
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Disorders of Sex Development / immunology
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Disorders of Sex Development / veterinary*
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Dog Diseases / genetics*
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Dogs
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Female
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Genes
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Genetic Linkage
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Histocompatibility Antigens / genetics*
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Leukocytes / immunology
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Male
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Ovary / growth & development
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Testis / growth & development
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Y Chromosome / immunology
Substances
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Histocompatibility Antigens