Augmentin treatment of bacterial infections in hospitalised patients

N Z Med J. 1982 Aug 11;95(713):542-5.

Abstract

Twenty-five hospitalised patients were evaluated after treatment with oral augmentin (amoxycillin and clavulanic acid). Ten of 14 with respiratory tract, four of eight with urinary tract and five of five with miscellaneous infections (two with osteomyelitis, two typhoid carriers and one with typhoid fever) were cured. Three of four infections caused by amoxycillin resistant bacteria were cured. The drug was well tolerated even at relatively high clavulanic acid doses up to 1.0 g/day. Augmentin is a potentially useful antibiotic combination.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Amoxicillin / therapeutic use*
  • Amoxicillin-Potassium Clavulanate Combination
  • Anti-Bacterial Agents / therapeutic use*
  • Bacterial Infections / complications
  • Bacterial Infections / drug therapy*
  • Drug Combinations / therapeutic use
  • Drug Evaluation
  • Escherichia coli Infections / complications
  • Escherichia coli Infections / drug therapy
  • Female
  • Humans
  • Klebsiella Infections / complications
  • Klebsiella Infections / drug therapy
  • Male
  • Middle Aged
  • Penicillin Resistance
  • Proteus Infections / complications
  • Proteus Infections / drug therapy
  • Respiratory Tract Infections / drug therapy
  • Respiratory Tract Infections / etiology
  • Urinary Tract Infections / drug therapy
  • Urinary Tract Infections / etiology
  • beta-Lactamase Inhibitors

Substances

  • Anti-Bacterial Agents
  • Drug Combinations
  • beta-Lactamase Inhibitors
  • Amoxicillin-Potassium Clavulanate Combination
  • Amoxicillin