Glycosphingolipids of normal and leukemic human leukocytes

Mol Cell Biochem. 1982 Sep 3;47(2):81-95. doi: 10.1007/BF00234409.

Abstract

We have reviewed the studies on neutral glycosphingolipids and gangliosides of normal and leukemia human leukocytes. In this review, we examine (a) the glycosphingolipid composition of various leukocyte populations, (b) the differences in glycosphingolipids found among subsets of these cells, (c) the possible use of these compounds as markers of differentiation, and (d) the changes in glycosphingolipid composition that occur with leukemogenesis.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Acute Disease
  • B-Lymphocytes / analysis
  • Chemical Phenomena
  • Chemistry
  • Chromatography, High Pressure Liquid
  • Chromatography, Thin Layer
  • Chronic Disease
  • Gangliosides / blood
  • Glycosphingolipids / blood*
  • Humans
  • Leukemia / blood*
  • Leukocytes / analysis*
  • T-Lymphocytes / analysis

Substances

  • Gangliosides
  • Glycosphingolipids