Microdosimetry of Internally Deposited Radionuclides

Int J Appl Radiat Isot. 1982 Nov;33(11):967-79. doi: 10.1016/0020-708x(82)90228-9.

Abstract

Microdosimetry uses the physical interaction of ionization events with cellular targets and the modification of the direct effects by biological processes to explain the effects of radiation. Knowledge of sensitive sites inside cells, of microscopic distributions of internally deposited radionuclides, and distribution of energy deposition contribute to the understanding of radiation effects. The location and form of radionuclides within cells and organs in laboratory animals can be used to estimate radiation dose distributions and effects in humans.

Publication types

  • Review

MeSH terms

  • Animals
  • Bone and Bones / radiation effects
  • Cell Survival / radiation effects
  • DNA / radiation effects
  • Female
  • Humans
  • Liver / radiation effects
  • Lung / radiation effects
  • Male
  • Neoplasms, Radiation-Induced
  • Ovary / radiation effects
  • Radiation Dosage*
  • Radioisotopes*
  • Testis / radiation effects
  • Thyroid Gland / radiation effects

Substances

  • Radioisotopes
  • DNA