Evaluation of the antitumour activity of the non-steroidal antioestrogen monohydroxytamoxifen in the DMBA-induced rat mammary carcinoma model

Eur J Cancer. 1980 Feb;16(2):239-51. doi: 10.1016/0014-2964(80)90156-5.
No abstract available

Publication types

  • Comparative Study

MeSH terms

  • 9,10-Dimethyl-1,2-benzanthracene
  • Animals
  • Castration
  • Dose-Response Relationship, Drug
  • Estradiol / metabolism
  • Female
  • Mammary Neoplasms, Experimental / chemically induced
  • Mammary Neoplasms, Experimental / drug therapy*
  • Organ Size / drug effects
  • Promegestone / metabolism
  • Rats
  • Tamoxifen / analogs & derivatives*
  • Tamoxifen / therapeutic use
  • Uterus / drug effects
  • Uterus / metabolism

Substances

  • Tamoxifen
  • afimoxifene
  • Estradiol
  • 9,10-Dimethyl-1,2-benzanthracene
  • Promegestone