Ophthalmic sequelae of infantile hemangiomas of the eyelids and orbit

Am J Ophthalmol. 1978 Jun;85(6):806-13. doi: 10.1016/s0002-9394(14)78109-7.


The major findings in a study of 51 infants and children with infantile hemangioma of the eyelid were as follows: Visual complications occurred in 27 patients. The most common complications were amblyopia (in 22) and strabismus (in 17). Amblyopia of 6/60 (20/200) or less was probably caused by stimulus-deprivation, but amblyopia in the range of 6/30 (20/100) to 6/12 (20/40) was likely caused by anisometropia or strabismus. Eyelid occlusion of six months or more invariably resulted in amblyopia of 6/60 (20/200) or less. Occlusion for even one month carried a risk of amblyopia. Each child must be considered individually for therapy, which must be started as early as possible. Patients should receive careful follow-up from the beginning to prevent severe amblyopia. For difficult cases, we need more efficacious, safe methods to induce regression of these tumors.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Amblyopia / etiology*
  • Child
  • Eyelid Neoplasms / complications*
  • Eyelid Neoplasms / pathology
  • Female
  • Hemangioma / complications*
  • Hemangioma / pathology
  • Humans
  • Infant
  • Male
  • Orbital Neoplasms / complications*
  • Orbital Neoplasms / pathology
  • Sex Factors
  • Strabismus / etiology*
  • Visual Acuity