Generalized fibrosis of the extraocular muscles

Am J Ophthalmol. 1978 Jun;85(6):822-9. doi: 10.1016/s0002-9394(14)78112-7.


We studied four patients with the general fibrosis syndrome. One patient had bilateral inguinal hernias and unilateral cryptorchism; the other patients had no other congenital abnormalities. The patients developed normally both neurologically and metally. We successfully treated amblyopia and achieved good functional and cosmetic results with strabismus and blepharoptosis surgery. Histopathologic study revealed fibrous infiltration of extrinsic eye muscle and Tenon's capsule without inflammatory changes.

Publication types

  • Case Reports

MeSH terms

  • Amblyopia / surgery
  • Blepharoptosis / surgery
  • Child
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Muscular Diseases / diagnosis
  • Muscular Diseases / pathology
  • Muscular Diseases / surgery
  • Oculomotor Muscles* / pathology
  • Oculomotor Muscles* / surgery
  • Strabismus / surgery
  • Surgery, Plastic
  • Syndrome