Inhibition of polyamine biosynthesis by alpha-difluoromethyl ornithine potentiates the cytotoxic effects of arabinosyl cytosine in HeLa cells

Biochem Biophys Res Commun. 1980 Jul 16;95(1):423-30. doi: 10.1016/0006-291x(80)90755-x.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Carboxy-Lyases / antagonists & inhibitors*
  • Cell Cycle / drug effects*
  • Cell Division / drug effects
  • Cell Survival / drug effects
  • Cytarabine
  • Drug Synergism
  • Eflornithine
  • HeLa Cells
  • Humans
  • Ornithine / analogs & derivatives*
  • Ornithine / pharmacology
  • Ornithine Decarboxylase Inhibitors*
  • Polyamines / biosynthesis*

Substances

  • Ornithine Decarboxylase Inhibitors
  • Polyamines
  • Cytarabine
  • Ornithine
  • Carboxy-Lyases
  • Eflornithine