Abstract
The 3' terminal nucleotide sequence of two clones containing DNA complementary to mu chain mRNA of IgM-secreting cells has been determined. The sequence shows a termination codon (UGA) adjacent to the terminal tyrosine codon for the secreted protein and a 3' non-coding region of at least 106 bases. The primary translation product of this mu chain mRNA seems to terminate at the tyrosine of the secreted protein.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Animals
-
Base Sequence
-
Cloning, Molecular
-
Codon
-
DNA, Recombinant*
-
Immunoglobulin Heavy Chains / genetics*
-
Immunoglobulin M / genetics*
-
Immunoglobulin mu-Chains / genetics*
-
Mice
-
Peptide Chain Termination, Translational
-
RNA, Messenger / genetics*
Substances
-
Codon
-
DNA, Recombinant
-
Immunoglobulin Heavy Chains
-
Immunoglobulin M
-
Immunoglobulin mu-Chains
-
RNA, Messenger