Immunoassay of human tear lysozyme

Am J Ophthalmol. 1980 Nov;90(5):715-8. doi: 10.1016/s0002-9394(14)75143-8.


We used a single radial immunodiffusion technique to determine the lysozyme content of human tears. The level in healthy subjects with this method was 1.3 mg/ml of tears. In patients with trachoma, the level was low, 0.9 mg/ml of tears. Detecting the reduction in lysozyme level in patients with trachoma proved the utility of this method.

MeSH terms

  • Adolescent
  • Adult
  • Female
  • Humans
  • Immunodiffusion / methods
  • Male
  • Middle Aged
  • Muramidase / analysis*
  • Muramidase / immunology
  • Tears / enzymology*
  • Trachoma / enzymology*


  • Muramidase