Depletion of 9L rat brain tumor cell polyamine content by treatment with D,L-alpha-difluoromethylornithine inhibits proliferation and the G1 to S transition

Exp Cell Res. 1981 Jan;131(1):209-16. doi: 10.1016/0014-4827(81)90420-1.
No abstract available

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Brain Neoplasms
  • Cell Division / drug effects*
  • Cell Line
  • Dose-Response Relationship, Drug
  • Eflornithine
  • Interphase / drug effects*
  • Ornithine / analogs & derivatives*
  • Ornithine / pharmacology
  • Polyamines / metabolism*
  • Putrescine / metabolism
  • Putrescine / pharmacology
  • Rats
  • Spermidine / metabolism
  • Spermine / metabolism

Substances

  • Polyamines
  • Spermine
  • Ornithine
  • Spermidine
  • Putrescine
  • Eflornithine