Hydroa vacciniforme

Arch Dermatol. 1978 Aug;114(8):1193-6.


Two patients with hydroa vacciniforme, a rare photodermatosis of unknown etiology, demonstrated distinctive scarring and vesiculobullous skin lesions on light-exposed body areas. Results of blood and urine porphyrin studies were normal, and no systemic abnormalities were noted. A small bullous lesion was produced in normal skin in case 1 with 15 times the minimal erythema dose of ultraviolet energy. The conditions of both patients improved while they were taking beta carotene orally.

Publication types

  • Case Reports
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Carotenoids / therapeutic use
  • Child
  • Female
  • Humans
  • Hydroa Vacciniforme / complications
  • Hydroa Vacciniforme / drug therapy
  • Hydroa Vacciniforme / pathology*
  • Light / adverse effects
  • Male
  • Photochemotherapy
  • Photosensitivity Disorders / complications
  • Porphyrins / urine
  • Ultraviolet Rays / adverse effects


  • Porphyrins
  • Carotenoids