Two cases of segmental, small-intestinal lipomatosis are described. In both, the patients had crampy abdominal pain secondary to partial intestinal obstruction. A review of the literature uncovered reports of 16 similar cases, in some of which virtually the entire small intestine was involved. Diverticulosis and intussusception are associated lesions. Diagnosis may be made by an abnormal roentgenographic pattern. Provided the bowel is not so extensively involved that complete resection is impractical, surgical removal of the affected segment results in cure.